Sunday, March 22, 2009

Seroquel



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Former AstraZeneca U.S. S. Charles Schulz attended a national medical conference to present favorable research on a new psychiatric drug called Seroquel. Schulz, chief of psychiatry at the University of Minnesota, reported that the drug was 'significantly superior' to the old

AstraZeneca - Seroquel: the case of the missing diabetics

Shortly after new antipsychotic drugs came on the market in the late 1990s, the Food and Drug Administration started to worry that they might trigger diabetes in some patients. So in 2000, the FDA asked AstraZeneca P.L.C. and other pharmaceutical companies to share data on cases of new-onset diabete...

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The lawsuits filed against AstraZeneca over risks associated with the drug throws up an interesting sidelight on the practice of ghostwriting. Back in 2005, according to the British Medical Journal and the Guardian, AstraZeneca via medical writing The anonymous blogger on the Clinical Psychology and Psychiatry blog has been hard at work on the story of how research on Seroquel (quetiapine, by AstraZeneca) was manipulated and oversold. His latest effort is here . Once again, a major theme is how a "key opinion leader," that is, a prominent medical academic lavishly paid as a consultant or speaker, became overly enthusiastic about his employer's product. Unforunately, academic medicine is now rife with well-paid key opinion leaders.

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